Example plot for RET driver gene
The image linked here shows the correlation between low imbalance values and samples that do not contain a fusion (in red). Samples that contain a fusion (in blue) all contain higher imbalance values.
Zoomed in view:
A 3'/5' Imbalance value of 0.045 or greater indicates the likely presence of a RET fusion.
With a 3'/5' Imbalance value of 0.03, there is no evidence that a RET fusion is present.
The range of 3'/5' Imbalance values between 0.045 and 0.03 is an area of uncertainty where there is some evidence that a fusion may be present. The higher the imbalance values, the more evidence there is that a RET fusion is present.