Legal

Pub. No. MAN0018031  Rev.  A.0

September  9 2019  1:42:58.217



Life Technologies Holdings Pte Ltd | Block 33 | Marsiling Industrial Estate Road 3 | #07-06, Singapore 739256

The information in this guide is subject to change without notice.

DISCLAIMER: TO THE EXTENT ALLOWED BY LAW, THERMO FISHER SCIENTIFIC INC. AND/OR ITS AFFILIATE(S) WILL NOT BE LIABLE FOR SPECIAL, INCIDENTAL, INDIRECT, PUNITIVE, MULTIPLE, OR CONSEQUENTIAL DAMAGES IN CONNECTION WITH OR ARISING FROM THIS DOCUMENT, INCLUDING YOUR USE OF IT.

Revision history: Pub. No. MAN0018031

Revision

Date

Description

A.0

September 7, 2019

  • New features:

    • Sequence Variant Baseline creation

    • Audits of user activities, and changes made to software

    • Add an electronic signatures to reports

    • QC Metrics included in Final Report template

    • Molecular coverage analysis metrics included in QC Reports

    • Coverage analysis metrics included in QC Reports

    • Updates to administrative policies for system access password policies

    • Updates to information about transcript sets

    • New classification terms for variants

    • Notes can be added to completed analyses

    • New sample attributes: Mouse, Population, Sample Collection date and Sample Collection date

    • New API call: Get current results TSV

    • Updates to the Oncomine™ Variant Annotator plugin

    • Ability to upload list of genes for use with filter chains

    • New predefined filter chain for Extended Oncomine™ results

    • Tumor Mutational Burden (TMB) improvements

    • Parameters for MicroSatelliteInstability (MSI) detection to accommodate assays and analysis workflows to release after Ion Reporter™ Software 5.12

    • Immune Repertoire—Haplotype attribute and algorithm updates for Immune Repertoire to allow adverse events to be predicted. New plots added to Immune Repertoire visualizations.

    • Enhanced ability to add visualized content to Final Reports and Final Report templates

    • Updates to 16S Metagenomics workflow—allows uploading of custom databases, use of different filter settings and parameters for one or more additional databases

  • Updates to BRCA workflows and visualizations: LongDel column added to BRCA Report, allows use of alternate transcript annotation for BRCA1 in Exon Deletion, improvements to BRCA graphics and visualizations.

  • Sections rewritten, enhanced, updated, and improved:

    • Updates to name change from "Ion Reporter™ Software on Thermo Fisher Cloud" to "Ion Reporter™ Software on Connect"

    • Import and Manage Samples

    • Manage analysis workflows

    • Analyses

    • Visualize analysis results with Ion Reporter™ Software

    • Create and view reports

    • Filters and Filter Chains

    • Appendix added for the Oncomine™ Variant Annotator plugin

    • Administer Ion Reporter™ Software

    • Fusions appendix

Important Licensing Information

These products may be covered by one or more Limited Use Label Licenses. By use of these products, you accept the terms and conditions of all applicable Limited Use Label Licenses.

TRADEMARKS

All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.