FATHMM Scores filter

This filter can be added to filter chains in the software to calculate Functional Analysis through Hidden Markov Models (FATHMM) Scores for coding variants, nonsynonymous single-nucleotide variants (nsSNVs), and noncoding variants. The specific filters are:

FATHMM Scores(85)

FATHMM Scores(89)

Filter conditions include the ability to set a range from 0.0 to 1.0 for the score. In addition, the range boundary values can be included or excluded, and unannotated variants can be included or excluded in filtered analysis results.

The filter calculates FATHMM scores for coding variants, nsSNVs, and noncoding variants.