IGH V-gene usage and Shannon Diversity
This is an example of an IGH spectratyping plot from an Oncomine™ BCR IGH‑LR Assay analysis. Circle color indicates the Shannon Diversity of clones having a particular variable gene-CDR3 nucleotide length combination. Portions of the repertoire containing highly expanded clones typically have a corresponding low Shannon Diversity value. You can further partition the clones by isotype in Ion Reporter™ Software with the buttons that are above the interactive spectratyping plot.