ExAC filters

These filters can be added to filter chains to detect rare gene variants for specific population groups in Ion Reporter™ Software. The filters are derived from the Exome Aggregation Consortium (ExAC) database. The specific filters are:

  • ExAC AAF

  • ExAC EAAF

  • ExAC EFAF

  • ExAC ENFAF

  • ExAC GAF

  • ExAC LAF

  • ExAC OAF

  • ExAC SAAF

Filter conditions include the ability to set a range from 0.0 to 1.0, to include or exclude boundary values from the ranges, and to include or exclude unannotated variants in filtered analysis results.

The filter detects rare gene variant results that align with the ExAC database, which can be included or excluded from filtered analysis results.