ExAC filters

These filters can be added to filter chains to detect rare gene variants for specific population groups in the software. The filters are derived from the Exome Aggregation Consortium (ExAC) database. The specific filters are:

  • ExAC AAF(031)

  • ExAC AAF(01)

  • ExAC EAAF(31)

  • ExAC EAAF(01)

  • ExAC EFAF(031)

  • ExAC EFAF(01)

  • ExAC ENFAF(31)

  • ExAC ENFAF(01)

  • ExAC GAF(31)

  • ExAC GAF(01)

  • ExAC LAF(31)

  • ExAC LAF(01)

  • ExAC OAF(31)

  • ExAC OAF(01)

  • ExAC SAAF(31)

  • ExAC SAAF(01)

Filter conditions include the ability to set a range from 0.0 to 1.0. In addition, the range boundary values can be included or excluded, and unannotated variants can be included or excluded in filtered analysis results.

The filter detects rare gene variant results that align with the ExAC database, which can be included or excluded from filtered analysis results.