Apply flags, notes, or classifications to variants of interest

You can contribute to the MyVariants databases for the organization by applying flags to variants in analysis results in Ion Reporter™ Software. We recommend that you first apply classifications and notes before selecting the MyVariants flags.

  1. Click the Analyses tab to open the list of analyses, then click an analysis of interest.

    The Analysis Results screen appears in Summary view.

  2. (Optional) In the  (Note) column, click  (Add) , click the Notes tab, then enter a note for the variant. When you are finished, click Add Note.
  3. In the  (Flag) column, expand (Flag list), then select the appropriate flag.




    The flag icon becomes orange in the row of the variant and the variant is added to the MyVariants database. Important is used to track variants that are relevant to the research.


    The flag icon becomes gray in the row of the variant and the variant is added to the MyVariants database. Ignore is often used to denote known false positives or false negatives, or variants that are not associated with the research area.


    All variants are marked None by default. Select None to remove an Important or Ignore flag and to remove a variant from the MyVariants database.

  4. (Optional) In the Classification column, you can select one of the following classifications for each variant of interest:
    • Unclassified

    • Unknown

    • Benign

    • Suspected Benign

    • Likely Benign

    • Deleterious

    • Suspected Deleterious

    • Pathogenic

    • Likely Pathogenic

    • VUS

    • Uncertain Significance

    • Technical Artifact

  5. To check that the variants were added, select the Analyses tab, then click MyVariants. The latest additions appear at the top of the table.

Variants that are labeled as Important or Ignore are added to the default MyVariants database, MyVariantsDb_hg19, if the analyses were run through predefined analysis workflows. To add variants to a different MyVariants database, create or select a custom MyVariants database in the Annotation step when you create, copy, or edit an analysis workflow.