Edit a MyVariants database

You can edit a MyVariants database in Ion Reporter™ Software.

IMPORTANT! Edits to MyVariants can affect the MyVariants settings that are made by other members of the organization if you are sharing a MyVariants database.

You can change the Important or Ignore flags that are associated with variants in a MyVariants database.

If you delete an analysis that includes a variant that is labeled as Important or Ignore, the MyVariants database is unaffected and the variant flags, notes, and classifications remain.

You can also add notes to variants in a MyVariants database.

  1. In the Analyses tab, click MyVariants.
  2. In the MyVariants table, select a specific MyVariants database from the list.
  3. Review the flags, notes and classifications for each variant, then update each of the options, if needed.
    1. In the  (Flag) column, expand (Flag list), then select the appropriate flag.
      Table 1.




      The flag icon becomes orange in the row of the variant and the variant is added to the MyVariants database.

      Important is used to track variants that are relevant to the research.


      The flag icon becomes gray in the row of the variant and the variant is added to the MyVariants database. Ignore is often used to denote known false positives or false negatives, or variants that are not associated with the research area.


      All variants are marked None by default. Select None to remove an Important or Ignore flag and to remove a variant from the MyVariants database.

    2. In the  (Note) column, click  (Add) , click the Notes tab, then enter a note for the variant. When you are finished, click Add Note
    3. In the Classification column, you can select one of the following classifications for each variant of interest: Unclassified, Unknown, Benign, Suspected Benign, Likely Benign, Deleterious, Suspected Deleterious, Pathogenic, Likely Pathogenic, VUS, Uncertain Significance, Technical Artifact.